Skinceuticals introduce their first antioxidant night concentrate
To help target accumulated signs of visible skin ageing caused by free radical damage, the skin requires a multi-pronged antioxidant approach for protection and correction. Supplemental antioxidant formulations—often containing L-ascorbic acid—need to be applied in the morning to help reinforce the skin’s natural protection against damaging free radicals generated from environmental sources, including UVA, UVB, infrared radiation, and pollution.
As the skin cannot naturally produce or store vitamin C, this may be applied topically through a broad-spectrum formulation, proven to absorb within the skin.
However, even the most potent formulations are not able to help protect the skin against all free radicals. Additional protection is needed.
The skin is able to produce its own natural internal antioxidants to help defend itself against accumulated free radical damage. Regulated by the NRF-2 protein, this system mediates the expression of 200 cytoprotective molecules responsible for neutralising excessive free radical damage and promoting skin’s self-repair. However, with age and on-going environmental aggressions, the skin’s natural protective mechanisms can lose efficiency, rendering skin vulnerable to the cumulative effects of free radical damage and the subsequent appearance of skin ageing. Now, new science has shown that certain ingredients can work to influence and support these internal mechanisms.
Resveratrol is a potent polyphenol antioxidant found in grapes, various berries, nuts, and other plant sources. Over the past 10 years resveratrol has garnered the reputation as the “longevity molecule,” owing to the role it has been found to play in determining species longevity and healthspan. It is believed that resveratrol works as an intracellular effector to modulate the signaling pathways responsible for age-related deterioration and functional decline.
Resveratrol has been scientifically shown to boost skin’s endogenous antioxidant defense via the NRF-2 pathway. By boosting this defense system, skin enhances its natural self-repair and rebuilds defenses against new damage.
Introducing Resveratrol BE
Resveratrol BE is SkinCeuticals’ first night-time ‘PREVENT’ formulation that helps to support the skin’s natural, endogenous defence system against free radical damage, to help repair the appearance of accumulated skin ageing. It also helps to strengthen skin’s functionality to help diminish the visible signs of accumulated skin damage.
Resveratrol BE combines our highest concentration of 1% pure, stable resveratrol—one of the highest levels available in a skincare formulation on the market today. Known to be difficult to stabilise within an aqueous solution, Resveratrol BE has been formulated with hydrotopes to ensure optimum absorption of the active ingredient. This is then synergistically enhanced with 0.5% baicalin and 1% alpha tocopherol.
Suitable for all skin types, Resveratrol BE should be applied at night after cleansing and is suitable to help target a variety of indications including signs of photodamage that have accumulated over time, overall loss of skin firmness and loss of skin radiance, poor elasticity and fine lines and wrinkles.
Resveratrol BE can also be recommended for use alongside invasive or non-invasive clinical treatments such as tightening and volumising procedures including radiofrequency or injectable treatments.
In a dermatologist controlled 12-week clinical trial conducted on 55 females with mild to moderate lines and wrinkles, Resveratrol BE was proven to be effective. Over the 12 weeks, different indicators of ageing were evaluated as improved vs the baseline, including skin radiance, skin firmness, skin smoothness, skin’s elasticity and skin density. Subjects applied Resveratrol BE once daily at night.
As shown by an ultrasound measurement, Resveratrol BE was also shown to help increase skin’s epidermal thickness by 18.9%.
SkinCeuticals will be exhibiting at this year’s FACE conference. Visit SkinCeuticals at stand 36-39 to find out more, or listen to an exclusive symposium ‘The latest developments within topical antioxidant formulations’ on Friday 20th June on the SKIN agenda.
Resveratrol B E will be available to order direct from SkinCeuticals, and from Wigmore Medical, from June 2014.
Features and benefits
• SkinCeuticals first antioxidant night concentrate
• Maximised concentration of pure, stable resveratrol
• Helps to reinforce skin’s natural endogenous defence system against free radical damage
• Scientifically proven to help improve the appearance of skin radiance, elasticity and density
• Complements daily SkinCeuticals vitamin C formulations, such as CE Ferulic and Phloretin CF, for comprehensive skin protection